1½cupsfreshly grated Parmesan or Kasseri cheese, divided
2large eggs, beaten
⅔cupplain Greek yogurt
For the Pasta
12ouncesbucatini, penne, or ziti
Instructions
Make the Meat Sauce
In a large pot, heat the olive oil over medium-high heat. Add the onion and sauté until translucent, about 4–5 minutes.
Add the ground beef and cook, breaking it apart with a wooden spoon, until no longer pink.
Stir in the red wine and cook for about 2 minutes. Add the garlic, cinnamon, oregano, thyme, and cayenne. Continue cooking over medium heat for 3–4 minutes.
Add the crushed tomatoes and season with salt and black pepper. Simmer over low heat, stirring occasionally, for 30 minutes. Set aside.
Make the Béchamel
Preheat the oven to 350°F (175°C). Heat the half-and-half in a small saucepan over medium-low heat until simmering, or warm it in the microwave.
In a medium saucepan, melt the butter. Whisk in the flour and cook over medium heat for about 2 minutes, whisking constantly.
Gradually add the warm half-and-half while whisking constantly. Continue cooking, stirring frequently, until thickened, about 5–6 minutes. Season with nutmeg, salt, and black pepper.
Stir in ¾ cup of grated cheese and approximately ½ cup of the meat sauce. Remove from the heat and cool for about 10 minutes.
Whisk in the beaten eggs, then add the Greek yogurt and mix until combined.
Assemble and Bake
Cook the pasta in a large pot of salted boiling water until just al dente. Drain.
Toss the pasta with the remaining meat sauce and transfer to a 9½ × 13-inch baking dish with enough depth to accommodate the topping.
Spread the béchamel over the pasta and sprinkle with the remaining ¾ cup of grated cheese.
Bake for 1 hour, or until golden brown and bubbly. Rest for 10 minutes before cutting and serving.
Notes
Pasta: Short penne or ziti works well if traditional Greek tubular pasta is unavailable.
No wine, no problem: Substitute beef or chicken broth for the red wine if preferred.
Ground Meat: You can substitute the lean ground beef with ground lamb or a combination of both. Ground chicken or turkey can also be used.
Don't Overcook the Pasta: Cook the pasta just until al dente, remember that the pasta will soften during baking.
Make-Ahead: Assemble the casserole up to 1 day in advance. Cover tightly and refrigerate. Remove it from the refrigerator 30-45 minutes before baking to take some of the chill off. A cold casserole may need additional oven time.
Prepare the Meat Sauce Ahead: The meat sauce can be made 1-2 days in advance and kept in an airtight container in the refrigerator.
Storage: Refrigerate leftover pastitsio in an airtight container for 3-4 days.
Freezing: Cool the baked casserole, wrap tightly, and freeze for up to 2 months. Individual portions are especially convenient for future meals.
Reheating: Thaw frozen pastitsio overnight in the refrigerator. Reheat covered in a 300°F (150°C) oven until heated through. Individual portions can also be reheated in the microwave.